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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b85bb8aeb5d1cd91079bd522fe687312c52c93a4e3b8be74af27a8afe0af80b' 
  AND token = 'kLy2Hy4xBIeSsSSJveeYmqvvptZ8VCOf10RAaCqmN9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}