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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d7a17c63feb7376509485dd14baa7fbfb01a0802ad543a33e8f3f0f0af71734' 
  AND token = 'FRJ4Yrt9KF2mHq6wNcrYQ6oJSEYeydF94N3LUQmXkW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}