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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72785f5f94e6a84d61f349297aa6ad0f278f1f5950166a6be64f55ebf6f8fe9f' 
  AND token = 'NNorz9wE9GdRoRKSi26okUtUAnS9AqalNaBcsRJnlYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}