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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e69f4ec7afb4ef9475660739969b0f9f81e8d9fa9e680f62a1883857b5abedd' 
  AND token = 'wM6Lu06SZyevqpbSj0XcLxk7HXFEJGEmbW7FOds7XjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}