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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccb10cc37d3af711f190cc934ed397fdd9219ff8e6018cbcebe9fa40d22300c7' 
  AND token = '+WBMjGt593Swxv8gw+aKORGx1xwXQZI+MmGDJnPaBO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}