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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '120d61865e487dde360892d9af34de6e20dd3a481e02934a90eb336b22c5f1d3' 
  AND token = 'RqE/2go3A6FT2LW6reAJ3akIVYrndThJ8e11YnPhBQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}