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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5154bd43a4f7700afcbba5b36b43804b25bc7a9014fcfbab134e57b0d130320c' 
  AND token = '6S0bm0w1VK3+0EiR2uKFZqkKuTQxYhxT4qazNr9xDMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}