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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '349007967c2df64e483c8236df34bed98e3a99d5f9a178869c777ac14abcefd3' 
  AND token = 'lgUazAW85F7Qb96z7aZBkpqQYKHQU/rg6r+sFBdVibI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}