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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888fa4019b1830cbbb811beec5be73fb970d110e7cf752c1d8e44e3022f7571d' 
  AND token = 'I8xzFjHO6gt+4G2f9AE2MPfSdvbrRk4Z4fW/Jtlp4Xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}