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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54ac73123e68fcf056b3cea2621c19ed4080a3fd7f8eefaab8ce7d9b4065a543' 
  AND token = '7YT1mOA3U+MEMASjQLGg5emWejOhQHlShAU0JO6k6Wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}