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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2e1a3701db1d1c1e68899f5bd5c3f0a52c0e382e076bde8a987a10b7a1d638' 
  AND token = '7xEgXF8n2ECpjCvNS/eHerYePV3cUAMK4qB7enoLD8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}