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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6ba0a71a1de1205a53fe0b227c35cf43b4143fc73552e8331673412faf3ae5b' 
  AND token = 'tAkXAsJ7o0wWRd5MpV7wCVZJuJ0GlqjJskB/Ctbf25I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}