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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '586eba69b582e93511640f513a22cb0ffa7926fa06e25c43c86c91cae3b814eb' 
  AND token = 'BtdBT/DC97YyQYcDv1UyEeXfDYtIV4s0mpK6NjtDLrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}