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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee10f1020ac07ce8e1088b70535f52c175daae2b6755724c7a459b53c164e3fc' 
  AND token = 'eupmo7ZZkVWtHHoK3ibeLW+SVD78Np0CxjZOsbi2U2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}