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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '595baf09e2d629610e3e449857894b5145c151942df5780cb9945b5cab221cff' 
  AND token = '5FUY/+TTGn9HQtBZ5pSC5dinEowwsqHX7DUfw26ZKvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}