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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a8db8f6d789a096a342f789a2a1d8a5dffc9199829caef0fb1291f09d8b955' 
  AND token = 'EUKvZVxdFxaQJfzFCJSmxypd9ShrVklwl3iBcS7twIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}