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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '514b81705d43987851399ef42f1319d145af1826e7a88af21d46516a19ec410f' 
  AND token = '21SktCH0g3OpcGNby2qYRGPSr0/3vJaund/4Uo4kHmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}