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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0e4bf1b1b6c29544c8b2c5073702cc0226ddd56054308ae02989ebe5c11e442' 
  AND token = 'A/Uk5yq2+TnfodYMz2fJZPuq0Y76ZCZzooh31o+4LsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}