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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af45bf7989a71a5539f570876aabf4eea02bf10fdc375ed8338f770f8b2c2407' 
  AND token = 'hRhXk7Dn7EbmvvhpCR5V/6IALM51aid30E94YR4gPms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}