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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db9975aa80224263ce4a8c914052a0b8eb1a956ba1321dcea9d11ff37271b55e' 
  AND token = '1K3EMsGPK4WoPu+9+T+k8XrQO4oZdyLiDVuXr8avySY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}