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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a2018f9f3fb4dac442863b03ad6b7f18deff4f930bdba9f94af1a8dbcae6b6' 
  AND token = '8w7vgsZfHrtIXRexB2/RzheZUCeElYtOgF3YVsXPXAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}