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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd3566145f41a5988aa56d4cd25e064b8a85b733b8bb38f180d4928bf83f989c' 
  AND token = 'Mwfc1c6D9OURlo2+0Auh0KqZzHSstxpgVMlOaqmzfX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}