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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f3a29b338e3a4fa08aeae0b50aac14f471f079d6fd1520aa0d97241b135a6ce' 
  AND token = 'xeXHU2AJcFweaZ5W/dKinv9KaLxlKDkhrCczGkVnpjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}