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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d4cb085c64574c16b961dc37bea51451511b81feff9842102ed8d6ca289a401' 
  AND token = '4LzQRMLzlt4PfA9sA1Z/8jsPNIBTqLr4tLrm2q8GyI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}