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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df0c85e375018b1f7752e1e83041c223f7833d45bc5183ada8b1b3f5b1728fa' 
  AND token = 'w1OtTwQBuFNv8nmUAsSKG3plbh6o+FvrxNrUZjSLhao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}