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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c750f6d0e8681ea01f3adc146fbeaca85e3e17c44b2f8cdbe2e2e644d7cff53' 
  AND token = '+ifeBo9AHWuFOl5tH6gSfg94+R14AqfUxfwF3sfLLGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}