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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '825a3dfe30fc83a3b8747c56974a74f8940397011431586cdc26c7da0790ad13' 
  AND token = 'Lu1kFfuNlogovdgDfhHy/WxJhqpThIk8Oj/rWm8UWek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}