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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bf680293f1b9e4ce01e0c61ed42c1e9311907b492c139f7ca5d18ee3f22acab' 
  AND token = 'BqY/j7v4Eoi/fpZ5vVlMhzfV2S2/MCxEMdRlue6umu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}