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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218ff064bd6c8a59be07630aca7d8c82015db084d04eecb4df9e58798f759175' 
  AND token = 'xGEs4b5btdpbGUdIGRedSqKB/VHNpDws8IdQzBI6baA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}