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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c869b8a0791f3b5fc62749a05e66a9c4251431e501e0e90edf361f537576501' 
  AND token = 'Pf2ORgQ2Xii7MmJxT93ib4H6q5MqbyI3dyLvml0Y8pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}