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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffd265ae34a8ece205e86740394e7cc60d6e05b55ae69bd53a6598ba6b07c395' 
  AND token = 'HbJf9cyH+d7IeS0klQGPS1s2fnjVAMyCvhJrf1MFHQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}