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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67e641b1eb98aa10cac74b867b642309728b2b1846f1055dfc59cee1d982018d' 
  AND token = 'KhI+OGTH/bfunj6rLp9e8gIYaS2cHk6T/dTZms/sQ2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}