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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e0c8b3ed2c477916c03ecf20d83ab89e1a2bff7efa800f9cbdf518aca016584' 
  AND token = 'vEFt4QqXl94ZBO1FrwsjGU8Jz2s/goHGgSgEa6tsBOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}