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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e11e88497587feaa17d6b9afc6fe5ea856ba7edc01d7df612ac0c9365bcbd194' 
  AND token = 'flwxZ0Lkbq1ZsJRorqVBrIuq/LoG1iKxQUWwTo1e/8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}