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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d2f400f3ea050ed8656fb2210a31e70bb33d9f1a5263499301f1c331c699622' 
  AND token = 'fjKAeVgH590fH2D2NjU8DMN0guJFoftqN1vjuE5dbEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}