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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5e22d7d071179c853be3d7e065f2b7ede794c9797ff4c05ef48cc6b506c5727' 
  AND token = 'Fg+tc+Mb8edqjCaWIZ0Lj9/IAQdQfKFEYKXDfg/N9HI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}