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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7236a78d4c3797c44f5e987e19c2519bcd5e3be748ddc5ea9f4f427d8cbc1a28' 
  AND token = 'WqWrwiLxq08ndt5G8C+n4h/N2tfVKKqeT4wcaojK3/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}