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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05451cd0ad8dc38e9063e8d735a5c74cfacd89c77109cdae61bc078a4b6edb91' 
  AND token = 'osKhm9KmEC+q//fsnGtVVVcp2ujQvfe3JS0EMyZEWlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}