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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4355767c9a8abe06ad3a4b7d0f5285ddd11552b00260977a17e8cfe793b50b9' 
  AND token = 'nuLP9TChFQPAniuVCF01x3MJqPDnJOTOfrzrxeNBa9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}