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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f88974d38f47b68974632b53cf44fb14b2131430e9ba7a1572f4379d017559d' 
  AND token = 'AKm2cgI4AOzZ+lBKIH1pkjgVFtlP4ofwf9k+o3514oE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}