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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c4ec9a2386d60b527278fc7b0c415fee7581a4b1065408af3d9b3a68267b493' 
  AND token = 'Ikc5rnciAj5xkZmo7C9TXuUhXxnkqLwyoD9qXLugKK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}