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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5311f4af8506d448d1863d9420e945ac249c329cd5501498a2a902ea15365f3c' 
  AND token = 'KrsoZL2WJtckBxuDd4/VRyRXbTp55c8unvYVcN53qbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}