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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b1f226d309319fa4756e2f5ace47eec3f8da3f133afb4da4692dd1671305b65' 
  AND token = 'b7IecB+tlPLUAlwSZSHL8l3HUHs+avlYW6PvuZpWSJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}