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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '957e1e099b8e5bc5bfd1c2accc9d4735f0757554f3f193163733f569196950ad' 
  AND token = 'Wk+R0Ql6JTX7sep4tcqb0NXcbh2Pp1FUK3EeSznntAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}