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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a002db4e4d8842656c0024e6c8d936178f34c712a658857e3ada3d9ead3b833b' 
  AND token = 'ACMVhAFPMGvf1L2H1T/XxREgz+80WkcwroTX2OkK6mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}