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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b2eacbfca8944bce0c485c30c9cc6574ab7d3dfd653ae9c1a35966ee17842a3' 
  AND token = 'TKspZY6cIUEk1xdHQHLRqN6SvfSnqeBb+GrVGktrHE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}