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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2388556d20e97f30b5e5fbce924fa4a42f9a9331fe041e851d46e83a0e54dbd3' 
  AND token = 'QpOORB86HQ+Cier/at6qgKw6xy4yckVaGlVe9FllW8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}