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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e652d5c0ada218e9abaea87dd66ecfe46e978ec9d699c9c5c289a39d4436cf20' 
  AND token = 'pe1jnrlblcbB5D5EU/ULkcfANSELE+sWn5MxQ5xyIp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}