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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7edf0f1e1852f22655b3b402f29977760eb9d5eba8c459808464d09a2e89e882' 
  AND token = 'Tp/R0fGRk/E5RuFSuXrxAHGCLO1evn2VBeY5dCty7LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}