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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4825e5af243ea7a6ad54a6d674ce3636947ace96ac93be06a64527c2bd34aa86' 
  AND token = 'oZRVXdK6X8kUjdn9NWBnYPiVDk4tWk0wsg7yd4kAlZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}